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Goodwin model (biology) : ウィキペディア英語版 | Goodwin model (biology) In biology, the Goodwin model describes negative feedback oscillators in cellular systems,〔Goodwin, B. Oscillatory behavior in enzymatic control processes. Advances in Enzyme Regulation, 3, 1965, pages 425–428. 〕 for example, circadian rhythms or enzymatic regulation (such as lactose in bacteria). The Goodwin model, though, shows no stable limit cycles. limit cycles can exist, see references 〔M. Mincheva., M.R. Roussel., Turning-Hopf instability in biochemical reaction networks arising from pairs of subnetworks, Mathematical Biosciences, 240 (2012), 1-11〕 〔T. Saithong, K. Painter, A. Millar, The contributions of interlocking loops and extensive nonlinearity to the properties of the circadian clocks models, PLOS One 5 (2010) e13867. 〕 ==References==
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